Carprieve 100 mg tablets. Please note a prescription from your vet is required to purchase this product, Uses For analgesia and reduction of chronic inflammation, for example in degenerative joint disease, in dogs. Carprieve Tablets can also be used in the management of post-operative pain. An initial dose of 2 to 4 mg carprofen/kg bodyweight/day is recommended to be given as a single daily dose or in two equally divided doses. The dose may be reduced to 2 mg carprofen/kg bodyweight/day administered as a single daily dose after 7 days, subject to clinical response. Duration of treatment will be dependent upon the response seen. Long term treatment should be under regular veterinary supervision. To extend analgesic cover post-operatively, parenteral administration of carprofen, may be followed with Carprieve Tablets at 4mg/ kg/ daily for up to 5 days. Contraindictions, Warnings etc Do not use in cats. The elimination time of NSAIDs, including carprofen, in the cat is longer than in the dog and the therapeutic index is narrower. In the absence of specific data use in the cat is contra- indicated. Do not exceed the stated dose. Give with or after food. Do not use in dogs suffering from cardiac, hepatic or renal disease, where there is a possibility of gastrointestinal ulceration or bleeding, or where there is evidence of a blood dyscrasia or hypersensitivity to the product. As with other NSAIDs there is a risk of rare idiosyncratic renal or hepatic adverse effects. Typical undesirable effects associated with NSAIDs, such as vomiting, soft faeces/diarrhoea, faecal occult blood, loss of appetite and lethargy have been reported. These adverse reactions generally occur within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal. Do not use in puppies less than 4 months. Use in aged dogs may involve additional risk. If such a use cannot be avoided, such dogs may require a reduced dosage and careful clinical management. Avoid use in any dehydrated, hypovolaemic or hypotensive dog, as there is a potential rise of increased renal toxicity. NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated. Do not use in case of hypersensitivity to active substance or to any of the excipients. Carprofen is highly bound to plasma proteins and compete with other highly bound drugs, which can increase their respective toxic effects. Do not use this veterinary medicinal product concurrently with or within 24 hours of other NSAIDs or concurrently with glucocorticoids. Concurrent administration of potentially nephrotoxic drugs should be avoided. Do not administer concurrently with anticoagulants. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Do not use in pregnant or lactating bitches. For breeding animals, do not use during reproduction period.