Advantage for Large Dogs 10 - 25kg Advantage, applied once each month, kills fleas on your cat fast and breaks the flea life cycle. Simply squeeze the contents of the tube onto the skin on the back of your dog's neck. Advantage then spreads over your pet, remaining in the oily layer of the skin, where it is effective against fleas all month long. Best of all, fleas don't have to bite your dog to be affected, so with Advantage your pet suffers less of those painful flea bites. Advantage can also be used to control lice on dogs. The top 3 benefits of Advantage 1) Fast relief from painful bites Stops fleas biting in 3-5 minutes Advantage kills fleas on contact - they don't have to bite 2) Prevents development of further fleas Kills 98%-100% of fleas before they lay eggs Prevents infestation if your treated pet comes into contact with other pets with fleas Kills adult fleas and flea larvae within 20 minutes of contact 3) Long-lasting and easy to use Drop Advantage on the back of your pet to protect them from fleas for four weeks